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Go About YAZ - Learn About YAZ Using YAZ - Info on Starting YAZ About PMDD - PMDD Facts About Birth Control - Learn More About Birth Control YAZ Tools - Body Diary & More

What is premenstrual dysphoric disorder (PMDD)?

YAZ® (drospirenone & ethinyl estradiol) is the ONLY birth control pill proven to treat the emotional and physical symptoms of premenstrual dysphoric disorder (PMDD) in women who choose the Pill for birth control. YAZ is not for the treatment of premenstrual syndrome (PMS).

PMDD symptoms can include

  • Anger
  • Irritability
  • Markedly depressed moods
  • Feeling anxious
  • Bloating
  • Change in appetite
  • Headaches
  • Muscle aches

PMDD can severely impact your personal and professional life

PMDD is a mood disorder related to the menstrual cycle. PMDD significantly interferes with work or school, or with usual social activities and relationships with others. Symptoms include markedly depressed mood, anxiety or tension, mood swings, and persistent anger or irritability. Other features include decreased interest in usual activities, difficulty concentrating, lack of energy, change in appetite or sleep, and feeling out of control.

Physical symptoms associated with PMDD may include breast tenderness, headache, joint and muscle pain, bloating, and weight gain.

These symptoms occur regularly before menstruation starts and go away within a few days following the start of the period. Diagnosis of PMDD should be made by healthcare providers.

Think about it this way:

  • Have you missed multiple days of work or school due to your symptoms?
  • Do you find yourself always getting into fights with your significant other around the time of your period?
  • Do you experience markedly depressed moods or anxiety?

If you do find these situations common, you might want to talk to your healthcare provider about PMDD and how YAZ may help. Diagnosis of PMDD should be made by a healthcare provider. YAZ has not been shown to be effective for the treatment of premenstrual syndrome (PMS), a less serious cluster of symptoms occurring before menstruation. If you or your healthcare provider believes you have PMS, you should only take YAZ if you want to prevent pregnancy; and not for the treatment of PMS.

Go beyond birth control with YAZ

For women who choose the Pill for contraception, YAZ is the ONLY birth control proven to treat PMDD, a condition with emotional and physical premenstrual symptoms severe enough to impact your life.

What's more, in women who are able to and wish to use the Pill for birth control, YAZ may also help treat moderate acne.

Additional Resources

What if I have PMDD?

You're not alone and there is help

Talk with your healthcare provider about PMDD

Ask about YAZ and whether it may be right for you



Important Safety Information About YAZ®

What is YAZ Prescribed For? YAZ® (drospirenone & ethinyl estradiol) is indicated for:

  • The prevention of pregnancy in women who elect to use an oral contraceptive.
  • Treatment of the emotional and physical symptoms of premenstrual dysphoric disorder (PMDD) in women who choose to use an oral contraceptive as their method of contraception.
  • The effectiveness of YAZ for PMDD when used for more than 3 menstrual cycles has not been evaluated. YAZ has not been evaluated for the treatment of premenstrual syndrome (PMS).
  • Treatment of moderate acne vulgaris
  • In women at least 14 years of age, who have no known contraindications to oral contraceptive therapy and have achieved menarche. YAZ should be used for the treatment of moderate acne only if the patient desires an oral contraceptive for birth control.

Who Shouldn't Take Any Oral Contraceptives (OCs)? Some women should not use OCs, including women who have blood clots, certain cancers, a history of heart attack or stroke, as well as those who are or may be pregnant.

In Addition, Who Shouldn't Take YAZ? YAZ contains drsp®, a different kind of hormone that for some may increase potassium too much. Therefore, you should not take YAZ if you have kidney, liver, or adrenal disease because this could cause serious heart and health problems. Tell your doctor if you are on daily long-term treatment for a chronic condition such as cardiovascular disease or chronic inflammatory disease. Women who take certain drugs (see below) should have their potassium levels checked in the first month of taking YAZ.

What Drugs May Increase Potassium? NSAIDs-ibuprofen (Motrin®, Advil®), naproxen (Naprosyn®, Aleve®, and others) when taken long-term and daily for arthritis or other diseases or conditions, Potassium-sparing diuretics (spironolactone and others), Potassium supplementation, ACE inhibitors (Capoten®, Vasotec®, Zestril®, and others), angiotensin-II receptor antagonists (Cozaar®, Diovan®, Avapro®, and others), aldosterone antagonists, and heparin.

What Are The Risks Involved With Taking Any Oral Contraceptive (OC)? OCs can be associated with an increased risk of several serious cardiovascular side effects, including blood clots, stroke, and heart attack. Women, especially those 35 and over, are strongly advised not to smoke because it increases these risks. OCs do not protect against HIV infection or other STDs.

The most frequent (greater than 1%) side effects, which may or may not be related to YAZ, that were reported in all YAZ clinical trials included: upper respiratory infection, headache, breast pain, vaginal moniliasis, nausea, abdominal pain, dysmenorrhea, urinary tract infection, accidental injury, sinusitis, emotional lability, suspicious Papanicolaou smear, weight gain, depression, menstrual disorder, and asthenia.

The most frequent (greater than 1%) side effects, which may or may not be related to YAZ, that were either unique to each trial type or occurred in only two types of clinical trials included:

  • In the contraception trial: leukorrhea, diarrhea, vomiting, vaginitis, flu syndrome, moniliasis, allergic reaction, cystitis, tooth disorder, sore throat, infection, fever, surgery, back pain, migraine, dyspepsia, rhinitis, acne, gastroenteritis, bronchitis, pharyngitis, skin disorder, intermenstrual bleeding, decreased libido, pain, increased cough, dizziness, pain in extremity, and pelvic pain.
  • In the PMDD trials: intermenstrual bleeding, decreased libido, nervousness, menorrhagia, pain in extremity, migraine, vaginitis, hyperlipidemia, back pain, diarrhea, increased appetite, enlarged abdomen, and acne.
  • In the acne trials: metrorrhagia, flu syndrome, menorrhagia, gastroenteritis, tooth disorder, infection, vomiting, pharyngitis, sore throat, arthralgia, bronchitis, rhinitis, amenorrhea, and urine abnormality.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch,
or call 1-800-FDA-1088.

For Important risk and use information, please see the full patient prescribing information.

BAYER®, the Bayer Cross®, YAZ®, Aleve®, drsp® and Beyond Birth Control are trademarks of Bayer. All other trademarks are the property of their respective owners.

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