Comparison Chart

Important Safety Information About YAZ®

What is YAZ Prescribed For? YAZ® (drospirenone & ethinyl estradiol) is indicated for:

  • The prevention of pregnancy in women who elect to use an oral contraceptive.
  • Treatment of the emotional and physical symptoms of premenstrual dysphoric disorder (PMDD) in women who choose to use an oral contraceptive as their method of contraception.
  • The effectiveness of YAZ for PMDD when used for more than 3 menstrual cycles has not been evaluated. YAZ has not been evaluated for the treatment of premenstrual syndrome (PMS).
  • Treatment of moderate acne vulgaris
  • In women at least 14 years of age, who have no known contraindications to oral contraceptive therapy and have achieved menarche. YAZ should be used for the treatment of moderate acne only if the patient desires an oral contraceptive for birth control.

Who Shouldn't Take Any Oral Contraceptives (OCs)? Some women should not use OCs, including women who have blood clots, certain cancers, a history of heart attack or stroke, as well as those who are or may be pregnant.

In Addition, Who Shouldn't Take YAZ? YAZ contains drsp®, a different kind of hormone that for some may increase potassium too much. Therefore, you should not take YAZ if you have kidney, liver, or adrenal disease because this could cause serious heart and health problems. Tell your doctor if you are on daily long-term treatment for a chronic condition such as cardiovascular disease or chronic inflammatory disease. Women who take certain drugs (see below) should have their potassium levels checked in the first month of taking YAZ.

What Drugs May Increase Potassium? NSAIDs-ibuprofen (Motrin®, Advil®), naproxen (Naprosyn®, Aleve®, and others) when taken long-term and daily for arthritis or other diseases or conditions, Potassium-sparing diuretics (spironolactone and others), Potassium supplementation, ACE inhibitors (Capoten®, Vasotec®, Zestril®, and others), angiotensin-II receptor antagonists (Cozaar®, Diovan®, Avapro®, and others), aldosterone antagonists, and heparin.

What Are The Risks Involved With Taking Any Oral Contraceptive (OC)? OCs can be associated with an increased risk of several serious cardiovascular side effects, including blood clots, stroke, and heart attack. Women, especially those 35 and over, are strongly advised not to smoke because it increases these risks. OCs do not protect against HIV infection or other STDs.

The most frequent (greater than 1%) side effects, which may or may not be related to YAZ, that were reported in all YAZ clinical trials included: upper respiratory infection, headache, breast pain, vaginal moniliasis, nausea, abdominal pain, dysmenorrhea, urinary tract infection, accidental injury, sinusitis, emotional lability, suspicious Papanicolaou smear, weight gain, depression, menstrual disorder, and asthenia.

The most frequent (greater than 1%) side effects, which may or may not be related to YAZ, that were either unique to each trial type or occurred in only two types of clinical trials included:

  • In the contraception trial: leukorrhea, diarrhea, vomiting, vaginitis, flu syndrome, moniliasis, allergic reaction, cystitis, tooth disorder, sore throat, infection, fever, surgery, back pain, migraine, dyspepsia, rhinitis, acne, gastroenteritis, bronchitis, pharyngitis, skin disorder, intermenstrual bleeding, decreased libido, pain, increased cough, dizziness, pain in extremity, and pelvic pain.
  • In the PMDD trials: intermenstrual bleeding, decreased libido, nervousness, menorrhagia, pain in extremity, migraine, vaginitis, hyperlipidemia, back pain, diarrhea, increased appetite, enlarged abdomen, and acne.
  • In the acne trials: metrorrhagia, flu syndrome, menorrhagia, gastroenteritis, tooth disorder, infection, vomiting, pharyngitis, sore throat, arthralgia, bronchitis, rhinitis, amenorrhea, and urine abnormality.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For Important risk and use information, please see the full prescribing information.

BAYER®, the Bayer Cross®, YAZ®, Aleve®, drsp®, Beyond Birth Control and YAZXpress are trademarks of Bayer. All other trademarks are the property of their respective owners.

Important Safety Information about YAZ    Prescribing Information, including Boxed WARNING
YAZ is associated with increased risks of several serious side effects, including blood clots, stroke, and heart attack. Women, especially those 35 and over, are strongly advised not to smoke because it increases these risks. In addition, YAZ contains drospirenone, a different kind of hormone that for some may increase potassium too much. continue reading below
Go About YAZ - Learn About YAZ Using YAZ - Info on Starting YAZ About PMDD - PMDD Facts About Birth Control - Learn More About Birth Control YAZXpress - Get With the Program

Beyond birth control: Additional benefits of YAZ

For women who choose the Pill for contraception, YAZ® (drospirenone & ethinyl estradiol) goes beyond birth control with 3 indications.

YAZ is THE ONLY birth control indicated to treat emotional and physical premenstrual symptoms that are severe enough to impact your life, a condition called premenstrual dysphoric disorder (PMDD).

PMDD symptoms may include

  • Anger
  • Irritability
  • Markedly depressed moods
  • Feeling anxious
  • Bloating
  • Change in appetite
  • Headaches
  • Muscle aches

YAZ has not been shown to be effective for the treatment of premenstrual syndrome (PMS), a less serious cluster of symptoms occurring before menstruation. If you or your healthcare provider believes you have PMS, you should only take YAZ if you want to prevent pregnancy; and not for the treatment of PMS.

Treats moderate acne

In women who are able to and wish to use the Pill for birth control, YAZ is clinically proven to treat moderate acne.

While YAZ has helped many women with PMDD and moderate acne, you should know that it may not be for everyone.

YAZ contains a hormone that for some may increase potassium too much, so don't take YAZ if you have kidney, liver, or adrenal disease as this could cause serious heart and health problems.

Serious risks include blood clots, stroke, and heart attack.

Smoking increases these risks, especially if you're over 35.

Don't take the Pill if you've had any of these, certain cancers, or could be pregnant.

The Pill does not protect against HIV or STDs.

Get shorter, lighter periods with YAZ

YAZ, like most other birth control pills, can also help give you shorter, lighter periods, a more regular cycle, and even reduce your cramps. Lighter periods can mean less blood loss. This reduces iron loss and lowers the risk of iron-deficiency anemia.

YAZ is a combination birth control pill, containing both an estrogen and a progestin. So, like other combination birth control pills, it may also offer you many additional noncontraceptive health benefits, such as lighter, more regular periods.

Like other birth control pills, YAZ may also reduce the risk of:

  • Ovarian cysts
    Combination pills help prevent ovulation. When you are not ovulating, you have less risk of developing noncancerous or benign ovarian cysts
  • Noncancerous breast cysts or lumps
    If you are on a combination pill, you may be less likely to develop cysts or lumps in your breasts
  • Ectopic pregnancy
    An ectopic, or tubal pregnancy is one that develops outside the uterus, most often in the fallopian tubes. Using a combination pill may lower the occurrence of this life-threatening condition
  • Endometrial cancer
    Endometrial cancer occurs in the lining of the uterus (endometrium). Combination pills have been shown to reduce your risk from this kind of cancer.
  • Ovarian cancer
    Combination pills may help protect you from cancer of the ovaries.


What is YAZ Prescribed For? YAZ® (drospirenone & ethinyl estradiol) is indicated for:

  • The prevention of pregnancy in women who elect to use an oral contraceptive.
  • Treatment of the emotional and physical symptoms of premenstrual dysphoric disorder (PMDD) in women who choose to use an oral contraceptive as their method of contraception.
  • The effectiveness of YAZ for PMDD when used for more than 3 menstrual cycles has not been evaluated. YAZ has not been evaluated for the treatment of premenstrual syndrome (PMS).
  • Treatment of moderate acne vulgaris
  • In women at least 14 years of age, who have no known contraindications to oral contraceptive therapy and have achieved menarche. YAZ should be used for the treatment of moderate acne only if the patient desires an oral contraceptive for birth control.

Who Shouldn't Take Any Oral Contraceptives (OCs)? Some women should not use OCs, including women who have blood clots, certain cancers, a history of heart attack or stroke, as well as those who are or may be pregnant.

In Addition, Who Shouldn't Take YAZ? YAZ contains drsp®, a different kind of hormone that for some may increase potassium too much. Therefore, you should not take YAZ if you have kidney, liver, or adrenal disease because this could cause serious heart and health problems. Tell your doctor if you are on daily long-term treatment for a chronic condition such as cardiovascular disease or chronic inflammatory disease. Women who take certain drugs (see below) should have their potassium levels checked in the first month of taking YAZ.

What Drugs May Increase Potassium? NSAIDs-ibuprofen (Motrin®, Advil®), naproxen (Naprosyn®, Aleve®, and others) when taken long-term and daily for arthritis or other diseases or conditions, Potassium-sparing diuretics (spironolactone and others), Potassium supplementation, ACE inhibitors (Capoten®, Vasotec®, Zestril®, and others), angiotensin-II receptor antagonists (Cozaar®, Diovan®, Avapro®, and others), aldosterone antagonists, and heparin.

What Are The Risks Involved With Taking Any Oral Contraceptive (OC)? OCs can be associated with an increased risk of several serious cardiovascular side effects, including blood clots, stroke, and heart attack. Women, especially those 35 and over, are strongly advised not to smoke because it increases these risks. OCs do not protect against HIV infection or other STDs.

The most frequent (greater than 1%) side effects, which may or may not be related to YAZ, that were reported in all YAZ clinical trials included: upper respiratory infection, headache, breast pain, vaginal moniliasis, nausea, abdominal pain, dysmenorrhea, urinary tract infection, accidental injury, sinusitis, emotional lability, suspicious Papanicolaou smear, weight gain, depression, menstrual disorder, and asthenia.

The most frequent (greater than 1%) side effects, which may or may not be related to YAZ, that were either unique to each trial type or occurred in only two types of clinical trials included:

  • In the contraception trial: leukorrhea, diarrhea, vomiting, vaginitis, flu syndrome, moniliasis, allergic reaction, cystitis, tooth disorder, sore throat, infection, fever, surgery, back pain, migraine, dyspepsia, rhinitis, acne, gastroenteritis, bronchitis, pharyngitis, skin disorder, intermenstrual bleeding, decreased libido, pain, increased cough, dizziness, pain in extremity, and pelvic pain.
  • In the PMDD trials: intermenstrual bleeding, decreased libido, nervousness, menorrhagia, pain in extremity, migraine, vaginitis, hyperlipidemia, back pain, diarrhea, increased appetite, enlarged abdomen, and acne.
  • In the acne trials: metrorrhagia, flu syndrome, menorrhagia, gastroenteritis, tooth disorder, infection, vomiting, pharyngitis, sore throat, arthralgia, bronchitis, rhinitis, amenorrhea, and urine abnormality.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

For Important risk and use information, please see the full prescribing information.

BAYER®, the Bayer Cross®, YAZ®, Aleve®, drsp®, Beyond Birth Control and YAZXpress are trademarks of Bayer. All other trademarks are the property of their respective owners.

You are now leaving the www.yaz-us.com website.

Bayer HealthCare Pharmaceuticals Inc. is not responsible for the content presented by any independent website, including any advertising claims, special offers, illustrations, names or endorsements.

Thank you for visiting www.yaz-us.com.


You are leaving a Bayer HealthCare Pharmaceuticals, Inc. web site...

and going to a third party site to activate or download the Bayer Savings Card. That site may have a privacy policy different from Bayer HealthCare Pharmaceuticals, Inc.


Do you want to go to the third party site to activate or download a Bayer Savings Card?


The requested information is provided in Portable Document Format (PDF). To view and print this document you'll need to install a copy of the free Adobe® Acrobat® Reader®. If you already have Adobe Acrobat Reader installed click "VIEW PDF" below. If you need the Acrobat Reader you can download it from the Adobe Acrobat Reader Download page.
Don't show me this message again.